Using Cognition to Understand Effects of Medicines Used to Optimize Sleep or Wakefulness, Upcoming Webinar Hosted by Xtalks

In this free webinar, learn about the importance of measuring cognition in sleep medicine trials. Attendees will gain insights into the nature and magnitude of cognitive impairment that can occur in sleep medicine drug development. The featured speaker will discuss how cognitive tests can be used to better inform decision-making on safety and efficacy of novel and licensed drugs.

TORONTO, April 10, 2024 /PRNewswire-PRWeb/ -- Disruption to normal sleep/wake cycles results in substantial disability and loss of productivity. Sleep/wake cycle dysfunction can also increase morbidity and mortality and therefore remains an urgent target for the development of medicines that can ameliorate such dysfunction.

In the field of sleep medicine, the meaning of changes in cognition can be communicated using various terms such as fatigue, drowsiness, sleepiness, sedation, diminished alertness and diminished attention. Such variability reduces the ability of clinical teams to make decisions about the nature and magnitude of cognitive impairment in disorders of the sleep/wake cycle, the effects of sedative and alerting drugs in experimental medicine models and the best approach to utilize cognitive information in late-phase clinical trials.

In this webinar, Prof. Paul Maruff will utilize published cognitive test data obtained from many clinical trials and provide a framework for understanding the nature and magnitude of cognitive impairment that can occur in sleep medicine drug development. Data are obtained from trials of patients with disrupted sleep/wake cycles, healthy adults who have received medicines with sedative effects and healthy adults who have undergone long periods of sleep restriction. This framework will help research teams make informed decisions about the safety and efficacy of novel and licensed drugs in drug development programs.

Register for this webinar today to discover how data on cognition can provide insights into the cognitive impairment that may arise in sleep medicine drug development.

Join Paul Maruff, PhD, Chief Innovation Officer, Cogstate, for the live webinar on Tuesday, April 30, 2024, at 11am EDT (4pm BST/UK).

For more information, or to register for this event, visit Using Cognition to Understand Effects of Medicines Used to Optimize Sleep or Wakefulness.

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