Le Lézard
Subject: Proxy/Proxy Vote

JDS1, LLC Files Definitive Proxy Statement and Sends Letter to Catalyst Stockholders


JDS1, LLC, which collectively with the other participants in its solicitation beneficially owns approximately 8.4% of the outstanding common stock of Catalyst Biosciences, Inc. (NASDAQ: CBIO) ("Catalyst" or the "Company"), today announced that it has filed its definitive proxy statement with the U.S. Securities and Exchange Commission and sent a letter to its fellow stockholders. JDS1 is urging shareholders to vote on the GOLD proxy card to elect its slate of three highly-qualified nominees ? Shelly Lombard, Matthew Stecker, and Igor Volshteyn ? to Catalyst's eight-member Board of Directors at Catalyst's 2022 Annual Meeting of Stockholders to be held in person on August 15, 2022. In its letter to stockholders, included below, JDS1 again calls for Catalyst to firmly, and unequivocally, commit to a distribution to stockholders of most of its available cash at the earliest possible time.

Julian D. Singer, JDS1's Managing Member, commented: "Contrary to Catalyst's public protestations, our agenda is in pursuing this proxy contest is very clear. We are pursuing this proxy contest principally to ensure that the Catalyst Board takes timely, if not immediate, action to distribute the maximum amount of its available cash to ALL stockholders, including following through on Catalyst's very non-committal public statement, made in apparent response to our proxy contest, that it intends to, at some unspecified point in time, return "as much as" $65 million in cash to stockholders, with the total amount to be distributed dependent upon "several factors.""

A complete copy of JDS1's letter to Catalyst's stockholders follows:

July 21, 2022

Dear Fellow Catalyst Biosciences, Inc. Stockholder:

Enclosed you will find the proxy materials of JDS1, LLC for the 2022 Annual Meeting of the Stockholders of Catalyst Biosciences, Inc. to be held in person on August 15, 2022, at 8:00 a.m., Pacific Time, at 611 Gateway Boulevard, Suite 710, South San Francisco, California 94080.

We, together with the other participants in our solicitation, own approximately 7.6% of Catalyst's outstanding common stock, making us one of Catalyst's largest stockholders. As a fellow Catalyst stockholder, we are seeking your support and asking you to vote TODAY by signing, dating, and returning the enclosed GOLD proxy card in the postage-paid envelope provided and vote FOR ALL of JDS1's highly qualified and very experienced nominees ? Shelly C. Lombard, Matthew Stecker, and Igor Volshteyn. You may also vote by phone or Internet by following the instructions on the enclosed GOLD proxy card.

CATALYST IS AT A CRITICAL JUNCTURE AND THE BOARD MEMBERS WHO ARE ELECTED AT THE ANNUAL MEETING COULD HELP DETERMINE WHETHER THE COMPANY DISTRIBUTES THE MAXIMUM AMOUNT OF CASH TO STOCKHOLDERS

UNDER THE WATCH OF THE INCUMBENT BOARD MEMBERS,

CATALYST STOCKHOLDERS HAVE SUFFERED TREMENDOUS VALUE DESTRUCTION

WE BELIEVE THAT STOCKHOLDERS NEED TO QUESTION WHETHER THEY CAN TRUST THE INCUMBENT BOARD MEMBERS TO ENSURE THAT CATALYST DISTRIBUTES

THE MAXIMUM AMOUNT OF CASH TO STOCKHOLDERS

WE HAVE MADE NUMEROUS ATTEMPTS TO CONSTRUCTIVELY RESOLVE OUR CONCERNS WITH CATALYST, EVEN RECENTLY OFFERING TO DROP OUR STOCKHOLDER LITIGATION

IF CATALYST WOULD COMMIT TO A TIMELY CASH DISTRIBUTION

TO STOCKHOLDERS OF AT LEAST $60 MILLION

SUPPORT JDS1'S EFFORTS TO UNLOCK STOCKHOLDER VALUE AND DRIVE THE MAXIMUM DISTRIBUTION OF AVAILABLE CASH TO STOCKHOLDERS BY VOTING FOR JDS1'S THREE HIGHLY QUALIFIED NOMINEES ON THE GOLD PROXY CARD TODAY

We also urge you to discard any white proxy card or voting instruction card you may receive from Catalyst. Even a WITHHOLD vote with respect to Catalyst's nominees on its white proxy card will cancel any GOLD proxy card previously given to JDS1. If you previously signed a white proxy card sent to you by Catalyst, you can revoke that proxy card and vote for JDS1's nominees by voting a new GOLD proxy card. Only your latest-dated proxy card will count.

We urge you to carefully consider the information contained in the attached Proxy Statement and then support our efforts by signing, dating, and returning the enclosed GOLD proxy card today. If you have any questions or require any assistance with your vote, please contact Kingsdale Advisors, which is assisting us, at its address and toll-free numbers listed below.

We look forward to communicating further with you in the coming weeks.

Thank you for your support,

/s/ Julian D. Singer

Julian D. Singer

JDS1, LLC

About JDS1, LLC

JDS1, LLC is a value-oriented investment firm based in Fort Lee, New Jersey. JDS1 is led by Julian D. Singer.

Additional Information and Where to Find It

On July 19, 2022, JDS1, LLC and the other participants in its proxy solicitation filed a definitive proxy statement and an accompanying GOLD proxy card with the Securities and Exchange Commission in connection with its solicitation of proxies for Catalyst Biosciences, Inc.'s 2022 Annual Meeting of Stockholders. BEFORE MAKING ANY VOTING DECISION, INVESTORS AND STOCKHOLDERS ARE STRONGLY ENCOURAGED TO READ JDS1'S PROXY STATEMENT, THE ACCOMPANYING GOLD PROXY CARD, AND ANY AMENDMENTS AND SUPPLEMENTS THERETO, AND OTHER DOCUMENTS FILED BY JDS1 WITH THE SEC CAREFULLY AND IN THEIR ENTIRETY WHEN THEY BECOME AVAILABLE AS THEY WILL CONTAIN IMPORTANT INFORMATION. Information regarding the identity of participants, and their direct or indirect interests, by security holdings or otherwise, is set forth in JDS1's Proxy Statement, including the schedules thereto. Stockholders can obtain JDS1's Proxy Statement, any amendments or supplements to JDS1's Proxy Statement and other documents filed by JDS1 with the SEC for no charge at the SEC's website at www.sec.gov. Copies will also be available at no charge at the following website: http://www.myproxyonline.com/jds1. Investors can also contact JDS1's proxy solicitor, Kingsdale Advisors, toll free at 1-888-302-5677.



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