CAMBRIDGE, Mass., July 30, 2020 /PRNewswire/ -- Blueprint Medicines Corporation (NASDAQ:BPMC), a precision therapy company focused on genomically defined cancers, rare diseases and cancer immunotherapy, today reported financial results and provided a business update for the second quarter ended June 30, 2020.
"In recent months, we made substantial progress toward cementing Blueprint Medicines as the leading precision medicine company, presenting compelling clinical data for avapritinib and pralsetinib across multiple patient populations, entering into a global collaboration with Roche for pralsetinib and bolstering our financial position to create a path to self-sustainability," said Jeff Albers, Chief Executive Officer of Blueprint Medicines. "We are poised to build on these pillars of growth in the second half of 2020 as we continue to execute on our focused strategy. We look forward to delivering multiple precision therapies to patients in the near-term, while continuing to support the commercialization of AYVAKITtm (avapritinib) and investing in our broad portfolio of new innovative research programs."
Second Quarter 2020 Highlights and Recent Updates
Avapritinib: systemic mastocytosis (SM)
Avapritinib: gastrointestinal stromal tumor (GIST)
Pralsetinib: RET-altered cancers
BLU-263: systemic mastocytosis
Key Upcoming Milestones
The company expects to achieve the following near-term milestones:
Second Quarter 2020 Financial Results
Financial Guidance
Based on its current operating plans, Blueprint Medicines expects that its existing cash, cash equivalents and investments, together with the upfront payments under its collaboration with Roche and anticipated future product revenues, will provide sufficient capital to enable the company to achieve a self-sustainable financial profile.
Conference Call Information
Blueprint Medicines will host a live conference call and webcast at 8:30 a.m. ET today to discuss second quarter 2020 financial results and recent business activities. The conference call may be accessed by dialing (855) 728-4793 (domestic) or (503) 343-6666 (international), and referring to conference ID 2769677. A webcast of the call will be available under "Events and Presentations" in the Investors & Media section of the Blueprint Medicines website at http://ir.blueprintmedicines.com/. The archived webcast will be available on Blueprint Medicines' website approximately two hours after the conference call and will be available for 30 days following the call.
About Blueprint Medicines
Blueprint Medicines is a precision therapy company striving to improve human health. With a focus on genomically defined cancers, rare diseases and cancer immunotherapy, we are developing transformational medicines rooted in our leading expertise in protein kinases, which are proven drivers of disease. Our uniquely targeted, scalable approach empowers the rapid design and development of new treatments and increases the likelihood of clinical success. We have one precision therapy approved by the U.S. Food and Drug Administration and are currently advancing multiple investigational medicines in clinical development, along with a number of research programs. For more information, visit www.BlueprintMedicines.com and follow us on Twitter (@BlueprintMeds) and LinkedIn.
Cautionary Note Regarding Forward-Looking Statements
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, including, without limitation, statements regarding plans and timelines for the development of AYVAKITtm (avapritinib), pralsetinib, fisogatinib and BLU-263, including the timing, designs, implementation, enrollment, plans and announcement of results regarding Blueprint Medicines' ongoing and planned clinical trials; plans and timelines for submitting additional marketing applications for avapritinib and pralsetinib and, if approved, commercializing avapritinib for additional indications or in additional geographies or commercializing pralsetinib; the potential benefits of the FDA's RTOR program; the potential benefits of Blueprint Medicines' current and future approved drugs or drug candidates in treating patients; expectations regarding Blueprint Medicines' existing cash, cash equivalents and investments and the ability to achieve a self-sustainable financial profile; and Blueprint Medicines' strategy, goals and anticipated milestones, business plans and focus. The words "aim," "may," "will," "could," "would," "should," "expect," "plan," "anticipate," "intend," "believe," "estimate," "predict," "project," "potential," "continue," "target" and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Any forward-looking statements in this press release are based on management's current expectations and beliefs and are subject to a number of risks, uncertainties and important factors that may cause actual events or results to differ materially from those expressed or implied by any forward-looking statements contained in this press release, including, without limitation, risks and uncertainties related to the impact of the COVID-19 pandemic to Blueprint Medicines' business, operations, strategy, goals and anticipated milestones, including Blueprint Medicines' ongoing and planned research and discovery activities, ability to conduct ongoing and planned clinical trials, clinical supply of current or future drug candidates, commercial supply of current or future approved products, and launching, marketing and selling current or future approved products; Blueprint Medicines' ability and plans in establishing a commercial infrastructure, and successfully launching, marketing and selling current or future approved products; Blueprint Medicines' ability to successfully expand the approved indications for AYVAKIT or obtain marketing approval for AYVAKIT in additional geographies in the future; the delay of any current or planned clinical trials or the development of Blueprint Medicines' current or future drug candidates; Blueprint Medicines' advancement of multiple early-stage efforts; Blueprint Medicines' ability to successfully demonstrate the safety and efficacy of its drug candidates and gain approval of its drug candidates on a timely basis, if at all; the preclinical and clinical results for Blueprint Medicines' drug candidates, which may not support further development of such drug candidates; actions of regulatory agencies, which may affect the initiation, timing and progress of clinical trials; Blueprint Medicines' ability to develop and commercialize companion diagnostic tests for its current and future drug candidates; and the success of Blueprint Medicines' current and future collaborations, partnerships or licensing arrangements. These and other risks and uncertainties are described in greater detail in the section entitled "Risk Factors" in Blueprint Medicines' filings with the Securities and Exchange Commission (SEC), including Blueprint Medicines' most recent Annual Report on Form 10-K, as supplemented by its most recent Quarterly Report on Form 10-Q and any other filings that Blueprint Medicines has made or may make with the SEC in the future. Any forward-looking statements contained in this press release represent Blueprint Medicines' views only as of the date hereof and should not be relied upon as representing its views as of any subsequent date. Except as required by law, Blueprint Medicines explicitly disclaims any obligation to update any forward-looking statements.
Blueprint Medicines Corporation Selected Condensed Consolidated Balance Sheet Data (in thousands) (unaudited) | |||||
June 30, | December 31, | ||||
2020 | 2019 | ||||
Cash, cash equivalents and investments | $ | 650,273 | $ | 547,960 | |
Working capital (1) | 463,226 | 410,304 | |||
Total assets | 817,457 | 707,694 | |||
Deferred revenue | 44,705 | 46,073 | |||
Total liabilities | 236,090 | 243,335 | |||
Total stockholders' equity | 581,367 | 464,359 | |||
(1) Blueprint Medicines defines working capital as current assets less current liabilities. |
Blueprint Medicines Corporation Condensed Consolidated Statements of Operations Data (in thousands, except per share data) (unaudited) | |||||||
Three Months Ended | |||||||
June 30, | |||||||
2020 | 2019 | ||||||
Revenues: | |||||||
Product revenue, net | $ | 5,680 | $ | - | |||
Collaboration revenue | 2,663 | 5,110 | |||||
Total revenues | 8,343 | 5,110 | |||||
Cost and operating expenses: | |||||||
Cost of sales | 127 | - | |||||
Research and development | 91,079 | 87,101 | |||||
Selling, general and administrative | 42,174 | 21,923 | |||||
Total cost and operating expenses | 133,380 | 109,024 | |||||
Other income (expense): | |||||||
Interest income, net | 1,586 | 4,275 | |||||
Other income, net | (23) | (42) | |||||
Total other income | 1,563 | 4,233 | |||||
Net loss | $ | (123,474) | $ | (99,681) | |||
Net loss per share ? basic and diluted | $ | (2.28) | $ | (2.04) | |||
Weighted-average number of common shares used in net loss per share ? basic and diluted | 54,217 | 48,843 |
SOURCE Blueprint Medicines Corporation
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