Boundless Bio Announces Presentations at Two January Conferences
Boundless
Bio, a company interrogating and targeting extrachromosomal DNA
(ecDNA) in aggressive cancers, today announcedpresentations at
the following upcoming conferences:
2020
CTIC Pre-JPM 4th Healthcare Investment Summit: Scott
Moorefield, Ph.D., Chief Business Officer of Boundless Bio, will give
a company overview on Sunday, January 12, 2020, from 5:05 p.m. ? 5:20
p.m. PST.
Precision
Medicine World Conference: Jason Christiansen, Ph.D.,
Chief Technology Officer of Boundless Bio, will give a presentation
titled: "Targeting Extrachromosomal DNA (ecDNA), A New Approach To
Targeting Cancers With High Copy Number Amplification." The
presentation will take place during the Emerging Therapeutics Showcase
on January 24, 2020, at 2:15 p.m. PST.
About ecDNA
Extrachromosomal DNA, or ecDNA, are large circles of DNA containing
genes that are outside the cells' chromosomes and can make many copies
of themselves. ecDNA can be rapidly replicated within the cell, causing
high numbers of oncogene copies, a trait that can be passed to daughter
cells in asymmetric ways during cell division. Cells have the ability to
upregulate or downregulate ecDNA and resulting oncogenes to ensure
survival under selective pressures, including chemotherapy or radiation,
making ecDNA one of cancer cells' primary mechanisms of recurrence and
treatment evasion. ecDNA are rarely seen in healthy cells but are found
in many solid tumor cancers. They are a key driver of the most
aggressive and difficult-to-treat cancers, specifically those
characterized by high copy number amplification of oncogenes.
About Boundless Bio
Boundless Bio is a biotechnology company focused on interrogating a
novel area of cancer biology, extrachromosomal DNA (ecDNA), to deliver
transformative therapies to patients with previously intractable
cancers. For more information, visit www.boundlessbio.com.
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