This report offers market size & forecast data for cell & gene therapy market in Europe. The report covers commercial cell & gene therapy products, such as conventional cell therapies, CAR-T cell therapies, gene therapies, cell-based immunotherapies, and oncolytic virus therapies. Cell therapies sourced from mesenchymal stem cells, cell-based immune modulation therapies, and cell/tissue-based products derived from patients' blood are also covered in the report.
Tissue-engineered products and tissue grafts/scaffolds with synthetic mechanical structures are excluded from the scope of the report. This report provides a comprehensive and current market scenario of the Europe cell & gene therapy market, including the Europe cell & gene therapy market size, anticipated market forecast, relevant market segmentations, and industry trends.
The study considers a detailed scenario of the present cell and gene therapy market and its market dynamics for 2023-2028 in Europe. It covers a detailed overview of several market growth enablers, restraints, and trends. The report offers both the demand and supply aspects of the market. It profiles and examines leading companies and other prominent ones operating in the market.
MARKET DEFINITION
Cell and gene therapies are part of advanced therapy medicinal products (ATMPs). ATMPs are medicines that are developed based on genes, tissues and cells. The introduction of many novel ATMPs in recent years, especially cell and gene therapies changed the treatment dynamics of many complex and challenging diseases like cancer and genetic disorders. Government, as well as industrial and academic financing and collaboration among small and large biopharmaceutical companies, offer significant growth to the market in the coming years.
KEY HIGHLIGHTS
The Europe cell and gene therapy market was valued at $2.17 billion in 2022 and is projected to reach at $15.15 billion in 2028, with a compound annual growth rate (CAGR) of 38.20%, during the study period.
Among all commercial cell & gene therapies, Zolgensma is the first and only product to achieve the blockbuster drug tag. Zolgensma generated a revenue of $1.37 billion in 2022 and has the potential to reach around $5.00 billion by 2026.
Drug developers are prioritizing to develop and commercialize CAR-T cell-based gene therapies. Globally, more than 1,000 clinical trials are being conducted on CAR T-cell therapies, of which at least 500 clinical trials are for cancer alone. Kymriah (Novartis), Yescarta (Gilead Sciences), Tecartus (Gilead Sciences), Breyanzi (Bristol Myers Squibb), Abecma (Bristol Myers Squibb) and Carvykti (Janssen Biotech / Legend Biotech) are the commercial CAR-T therapies available in the market.
In 2022, Germany was the first-largest market in Europe, followed by France and the UK. The market is majorly driven by an increase in target patient population, regulatory body support, and higher access to healthcare due to well-established healthcare infrastructure.
The European Medicines Agency (EMA) has approved more than nineteen cell and gene therapy drugs, but the new product pipeline has approximately 193 investigational therapies, with more than half of these in Phase 2 clinical trials. Oncology and rare diseases continue to be the top areas targeted by gene therapies from preclinical through pre-registration.
Approximately 1,564 clinical trials are under investigation for various cell and gene therapies in Europe. This increase could be because of an improvement in funding for cell and gene therapy. The industry sponsored trials are continued to dominate with a share of 78.71%.
Novartis, Gilead Sciences, Spark Therapeutics, Amgen, Orchard Therapeutics, Bristol-Myers Squibb, BioMarin, PTC Therapeutics, and Organogenesis are the leading players in the Europe cell and gene therapy market. The market offers tremendous growth opportunities for existing and future/emerging players because of the presence of a large pool of target patient populations with chronic diseases such as cancer, genetic and rare diseases, and other complex disorders.
REPORT HIGHLIGHTS
PRODUCT SEGMENTATION & FORECAST
Product type
Cell therapy
Gene therapy
Application type
Oncology
Genetic Disorders
Dermatology
Musculoskeletal
Others
End-user type
Hospitals
Cancer Care Centers
Others
MARKET STRUCTURE
Approved Cell & Gene Therapies
Pipeline Analysis
Clinical Trial Analysis
Market Dynamics
Competitive Landscape of Cell & Gene Therapies
Key Vendors
Other Prominent Vendors
Key Topics Covered:
CHAPTER - 1: Cell & Gene Therapy Market Overview
CHAPTER - 2: Cell & Gene Therapy Market Segmentation Data
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