DUBLIN, May 24, 2022 /PRNewswire/ -- The "Global Acellular Therapy Market - Strategies and Applications: Focus on Application, Pipeline, and Competitive Landscape" report has been added to ResearchAndMarkets.com's offering.
This strategic report provides a multidimensional view of the strategic evolution of the ongoing acellular therapy initiatives. The purpose of the study is to gain a holistic view of the active acellular therapy projects implemented in several countries.
The report contains the analysis of variables such as recent trends, technological advancements, and international level initiatives across the globe influencing the adoption of acellular therapy.
The scope of this report is centered upon conducting a detailed study of the strategies, best R&D practices across the globe and understanding the focus of eminent stakeholders that are contributing to augmenting the growth of the acellular therapy initiatives.
Humans have a finite capacity for regeneration. The goal of regenerative medicine is to help an organism heal. Stem cell research has made remarkable progress, laying a strong foundation for its use in regenerative medicine applications of wounded or diseased tissues.
Stem cells (SCs) have been used to transplant into the damaged tissue as SCs live in humans for the remainder of their lives and can help differentiate into new stems and differentiated cells. SC transplantation has become the backbone of regenerative medicine. Intercellular communication between stem and differentiated cells has been a focus of regenerative medicine.
However, benefits from some stem cell therapies are related to paracrine actions rather than long-term engraftment and survival of transplanted cells. The benefits of stem cell therapy through paracrine actions have led to the development of a cell-free therapeutic method, also known as acellular therapy.
Acellular therapy based on stem cell therapy is expected to be used for promoting regeneration using bioactive chemicals. Intercellular communication between cells is now widely understood to occur through extracellular vesicles (EVs) and not just through soluble bioactive chemicals.
Recent research has focused on finding alternatives to cell-based therapy that involves paracrine elements. The utilization of soluble factors (secretome), extracellular vesicles, and mitochondrial transport can all be used to generate stem ""cell-free"" therapies. EVs are now being investigated as possible cell-free therapeutic agents due to their capacity to bypass biological barriers and promote intercellular information transmission of bioactive substances.
EVs are a heterogeneous set of lipid membrane-enclosed, double-layered vesicles with distinct biophysical properties and activities in physiology and pathology. Because of their ability to transport nucleic acids (including mRNAs and miRNAs), proteins, and lipids across cells, they are emerging as an important intercellular communication mediator. EVs can communicate with target cells in a variety of ways.
The potential use of EVs as therapeutic agents in acellular regenerative medicine has recently received great traction. Additionally, extracellular vesicles are being utilized to treat pathological circumstances and meet the acellular strategy's challenges and operational concerns.
Key Questions Answered in the Report
Key Topics Covered:
1 Acellular Therapy: Overview
2 Stem Cell Therapy
2.1 Extracellular Vesicles
2.2 Cell-Free Therapy with Extracellular Vesicles
3 Cell Therapy vs. Cell-Free Therapy
3.1 Advantages of Cell Therapy and Cell-Free Therapy
3.2 Risks and Limitations of Cell Therapy and Cell-Free Therapy
3.2.1 Challenges and Risks Associated with Stem Cell-Based Therapy in Regenerative Medicine
3.2.2 Challenges and Risks Associated with Cell-Free Therapies
4 Application of Extracellular Vesicles (EVs) in Regenerative Medicine
5 Acellular Therapy: A Novel Approach for COVID-19
5.1 COVID-19 Therapeutic Strategies Involving the MSC Secretome
5.2 Extracellular Vesicles Used in COVID-19 for Several Reasons
6 Expert Insights
7 Clinical Trial Analysis: Acellular Therapy
7.1 Acellular Therapy Pipeline Analysis
7.2 Acellular Therapy Clinical Trial Design
184.108.40.206 Product Profile
220.127.116.11 ExoFlo Phase II Study Design
8 Extracellular Vesicles-Based Therapeutics: Regulatory Aspects
8.1 Regulatory Frameworks in the U.S.
8.2 Regulatory Frameworks in Europe
8.3 Regulatory Frameworks in Canada
8.4 Regulatory Frameworks in Japan
8.5 Regulatory Frameworks in Australia
8.6 Regulatory Frameworks in South Korea
8.7 Challenges Prior to Clinical Translation
9 Competitive Landscape
9.1 Clinical Developments
9.2 Regulatory and Legal Activities
9.3 Partnerships and Alliances
9.4 Funding Activities
9.5 Business Expansions
10 Company Profiles
10.1 Company Overview
10.2 Role in the Acellular Therapy Market
10.3 Business Strategies
10.4 SWOT Analysis
For more information about this report visit https://www.researchandmarkets.com/r/epxoqb
Research and Markets
Laura Wood, Senior Manager
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