Le Lézard
Classified in: Health, Science and technology, Covid-19 virus
Subject: MRR

Gene and Cell Therapies Expected to Offer New Treatment Paradigm in CNS Disorders; Market Expected to Increase at a CAGR of 45% During the Study Period 2018-2026 in the 7MM


Targeting the root cause of various CNS Disorders, Gene and cell therapy hold promise as the next wave of innovation in the pharmaceutical industry

LAS VEGAS, July 26, 2021 /PRNewswire/ -- DelveInsight's 'Gene and Cell Therapies Targeting CNS Disorders ? Market Insights and Market Forecast ? 2026' report offers a panoramic view of the current treatment practices, emerging cell and gene therapies to treat CNS disorders, market share of the individual therapies, current and forecasted Gene and Cell Therapies Targeting CNS Disorders market in the 7MM (the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom), and Japan) for the study period  2018?2026. 

DelveInsight_Logo

 

Some of the focal points extracted from the Gene and Cell Therapies Targeting CNS Disorders Market report: 

Know more about the emerging therapy expected to penetrate the market significantly @ Gene and Cell Therapies Targeting CNS Disorders Market Insights, Pipeline Therapies, and Emerging Trends 

The report is created to project true opportunities in the Gene and Cell Therapies Targeting CNS Disorders market landscape, to help clients gain a competitive advantage over competitors, and to plan strategic moves to yield maximum ROI. 

CNS Disorders Burden

Central Nervous System (CNS) Disorders are one of the most prevailing and destructive disorders that are often poorly understood and have limited treatment options. It contributes to the highest disability-adjusted life years (DALYs) and is the second leading cause of death in the United States. The past three decades witnessed a substantial rise in the diagnosis of neurological disorders, which are further expected to increase in coming years. 

CNS diseases can arise as a concomitant condition due to complicated disorders like ischemic, hemorrhagic, neurodegenerative, inflammatory, developmental disorders, damage from an infection, a degenerative condition, stroke, a brain tumor, or can be inherited. 

Burden of death and disability because of CNS disorders is a major cause of concern primarily driven by global population growth and aging; a lack of understanding of the pathophysiology of the CNS disorders, underlying risk factors that may lead to CNS disorders and so on. 

Unmet Needs in the Market 

At present, there is no curative option available in the healthcare and pharmaceutical market, and the drug development of curative and effective therapies is hindered by several challenges.

First and foremost, the mechanisms of CNS diseases are quite difficult to understand because of a lack of complete understanding of the brain functioning, which inarguably is the most complicated organ in the human body. 

Secondly, the major barrier is imposed by a dearth of standard targets for the treatment of CNS disorders. Target or biomarker identification, in this case, appears quite challenging owing to apparent defects in synaptic communication and functional connectivity and a lack of knowledge on genetic causes that are behind the CNS disorders. Studies of the pathophysiology of CNS disorders have failed to generate any fruitful results owing to the heterogeneity of the diseases. 

As per the estimates, more than 98% of the smaller molecular drugs and almost 100% large molecular therapeutics fail to offer effective care in CNS Disorders owing to their inability to cross BBB. 

Want to know more? Get comprehensive insights @ Gene and Cell Therapies Targeting CNS Disorders 

Get customized solutions and expand your business in the Gene and cell therapy market in the emerging markets through Delveinsight's Pharma market consulting and customized solutions 

Gene and Cell Therapy Market

Just like any sector, Gene and cell therapy market also went into the stage of quiescent with the stoppage of trials and shifting of focus towards COVID-19 therapeutics and prophylactics development, however, the R&D restored its pace, and the year 2020 witnessed significant developments and approvals with the majority in oncology. 

Gene and Cell Therapies Targeting CNS Disorders Market Analysis

At present, numerous Cell and Gene Therapies (CGTs) are under different stages of clinical development indicated for most devastating CNS disorders such as Spinal injury, Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), Spinal cord injury (SCI), Amyotrophic lateral sclerosis (ALS), Multiple sclerosis (MS), Spinal muscular atrophy (SMA), and others. 

The major players such as BrainStorm Cell Therapeutics, Helixmith, Corestem, Q therapeutics, and others are investigating their therapies in Phase II and III stages of development for different CNS Disorders. 

Drop by @ Gene and Cell Therapies Targeting CNS Disorders to learn more about the recent strides in R&D in CGTs being developed to treat CNS Disorders 

Gene and Cell Therapies Targeting CNS Disorders Pipeline Therapies 

Therapy 

Company 

Indication

Phase

NurOwn 

BrainStorm Cell Therapeutics

Amyotrophic lateral sclerosis

III

NurOwn 

BrainStorm Cell Therapeutics

Multiple

Sclerosis/ Chronic Progressive

II

Engensis

Helixmith

Amyotrophic Lateral Sclerosis

II

HYNR-CS inj 

Corestem

Amyotrophic Lateral Sclerosis

I/II

Q-Cells

Q Therapeutics

Amyotrophic Lateral Sclerosis

I/II

VM202 

Helixmith

Amyotrophic Lateral Sclerosis

I/II

RAPA-501 Autologous T cells 

Rapa Therapeutics

Amyotrophic Lateral Sclerosis

I/II

Neuro-Cells 

Neuroplast

Spinal Chord Injuries

I & II/III

Umbilical Cord Blood Mononuclear Cell 

StemCyte

Spinal Chord Injuries

II

itMSCs 

Stemedica Cell Technologies

Alzheimer's Disease

II

AAV-hTERT

Libella Gene Therapeutics

Alzheimer's Disease

I

ST-501 

Sangamo Therapeutics

Alzheimer's Disease

Pre-clinical

VY-AADC 

Voyager Therapeutics

Parkinson's Disease. 

I & II

Lomecel-B 

Longeveron

Alzheimer's Disease

I

AXO Lenti PD

Axovent

Parkinson's Disease

II 

PR001 

Prevail Therapeutics

PD-GBA

I/II 

Neural Stem

Cell-Derived Neurons

NeuroGeneration

Parkinson's Disease

  II/III

AAV2-GDNF 

AskBio

Parkinson's Disease

I

Intra-striatal rAAV5-miHTT 

UniQure Biopharma

Huntington Disease

II

 

Have a walkthrough of the detailed profile of the budding therapies in the Gene and Cell Therapies Targeting CNS Disorders Market 

Gene and Cell Therapies possess the potential to offer significant therapeutic benefits to patients living with different CNS Disorders. 

Thus, Gene and Cell Therapies are extensively investigated, however, still the count of approved Cell Therapies-based CNS Disorder treatments remains considerably less. 

Know which Pharma player has the potential to emerge as the leader in Gene and Cell Therapies Targeting CNS Disorders Market 

Gene and Cell Therapies Targeting CNS Disorders Market: Way Ahead

The past two decades witnessed several drug delivery strategies ranging from the tight junction modulation and drug molecule modification to focusing on the strategies which are based on endogenous transcytosis and carrier-dependent transport systems, including both the nanoparticle- and cell-based deliveries,  under investigation to improve the therapeutic effect of therapies. 

Rampant advances in genome analysis, healthcare technologies, and assembly of larger patient cohorts have facilitated the successful genetic analyses of polygenic brain disorders. 

Novartis' Zolgensma itself costs around USD 2.125 million per patient, earning the tag of the world's costliest drug, however, the drug maker argues that the one-time therapy has a clear upper hand over the other therapies that build up the cost burden on the patients with time. 

Get in touch with our KOLs @ Gene and Cell Therapies Targeting CNS Disorders Market Landscape and know more about the factors driving and hampering the market growth

Scope of the Report 

Coverage: 7MM (the US, EU5, and Japan)

Study Period: 2018-26

Key Companies in the Gene and Cell Therapy Market: Novartis, BrainStorm Cell Therapeutics, Corestem, Q Therapeutics, Helixmith, Rapa Therapeutics, BrainStorm Cell Therapeutics, Neuroplast, StemCyte, Ferrer Internacional, Neuralstem, Ferrer Internacional, Stemedica Cell Technologies, Libella Gene Therapeutics, Sangamo Therapeutics, Hoffmann-La Roche, Longeveron, Sio Gene Therapies, Eli Lilly and Company, NeuroGeneration, Brain Neurotherapy Bio (AskBio), UniQure Biopharma, and others. 

Key Gene and Cell Therapies Targeting CNS Disorders Pipeline Therapies: Zolgensma, NurOwn, Engensis, HYNR-CS inj, Q Cells, VM202, RAPA-501 Autologous T cells, NurOwn, Neuro-Cells, Umbilical Cord Blood Mononuclear Cell, FAB117-HC, Human spinal cord stem cells, FAB117-HC, itMSCs, AAV-hTERT, ST-501, VY-AADC, Lomecel-B, OXB-102, PR001, Neural Stem Cell-Derived Neurons, AAV2-GDNF, Intra-striatal rAAV5-miHTT, and others. 

Analysis: Comparative and conjoint analysis of Gene and Cell Therapies Targeting CNS Disorders Emerging therapies

Tools used: SWOT analysis, Conjoint Analysis, Porter's Five Forces, PESTLE analysis, BCG Matrix analysis methods.

Case Studies

KOL's Views

Analyst's Views

Get in touch to know more about the report scope @ Gene and Cell Therapies Targeting CNS Disorders Market Analysis and Forecast 

Table of Contents

1

Key Insights

2

Report Introduction

3

Executive Summary

4

Gene and Cell Therapies Targeting CNS Disorders Market Overview at a Glance

5

Landscape Assessment

6

Gene and Cell Therapies Targeting CNS Disorders Marketed Therapies

7

Emerging Therapies for Amyotrophic Lateral Sclerosis

8

Emerging Therapies for Multiple sclerosis

9

Emerging Therapies for Spinal Cord Injury

10

Emerging Therapies for Alzheimer's Disease

11

Emerging Therapies for Parkinson Disease

12

 Emerging Therapies for Huntington

13

Company Profiles

14

Gene and Cell Therapies Targeting CNS Disorders: 7 Major Market Analysis

15

Market Outlook

16

Attribute analysis

17

 Key Opinion Leaders' Reviews

18

Gene and Cell Therapies Targeting CNS Disorders Market Drivers

19

Gene and Cell Therapies Targeting CNS Disorders Market Barriers

20

SWOT Analysis

21

Unmet Needs

21

Report Methodology

22

Appendix

23

Disclaimer

24

DelveInsight Capabilities

25

About DelveInsight

Know more about the report offerings @ Gene and Cell Therapies Targeting CNS Disorders Market Emerging Trends, Therapies and Revenue  

Related Reports 

Cerebral Palsy Market

DelveInsight's 'Cerebral Palsy - Market Insights, Epidemiology, and Market Forecast?2030' report.

Cervical Dystonia Market

DelveInsight's "Cervical Dystonia - Market Insights, Epidemiology, and Market Forecast-2030" report.

Chronic Neuropathic Pain Market

DelveInsight's "Chronic Neuropathic Pain Market Insights, Epidemiology, and Market Forecast-2030" report.

Cocaine Intoxication Market

DelveInsight's "Cocaine Intoxication Market Insights, Epidemiology, and Market Forecast-2030" report.

Concussions Market

DelveInsight's "Concussions Market Insights, Epidemiology, and Market Forecast-2030" report. 

Cerebral Palsy Market

DelveInsight's 'Cerebral Palsy Market Insights, Epidemiology, and Market Forecast?2030' report. 

Cervical Dystonia Market

DelveInsight's "Cervical Dystonia Market Insights, Epidemiology, and Market Forecast-2030" report.

Friedreich's Ataxia Market

DelveInsight's "Friedreich's Ataxia - Market Insights, Epidemiology, and Market Forecast-2030" report.

Frontotemporal Dementia Market

DelveInsight's "Frontotemporal Dementia - Market Insights, Epidemiology, and Market Forecast-2030" report.

Related Blogs 

Can Aducanumab Solve the Puzzle Of Alzheimer's?

The Alzheimer's Disease Market finally witnessed the approval of standard therapy, Aducanumab, by Biogen. What impact does it hold for the future?

Key Pharma Players Changing The Dynamics Of Schizophrenia Market

As per DelveInsight, the Schizophrenia market is expected to increase with a CAGR of 6.89% for the study period 2017-2030.

Gene and Cell Therapies in CNS Disorders: Miracle Cure? Opportunities Galore!

The key therapies currently in the development phase for different CNS indications are Amyotrophic lateral sclerosis: NurOwn (BrainStorm Cell Therapeutics), Engensis (Helixmith), Q cells (Q therapeutics), VM202 (Helixmith); Spinal cord injury: Neuro-Cells (Neuroplast), Umbilical Cord Blood Mononuclear Cell (StemCyte); Parkinson's disease: Axo Lenti PD (Axovant); Alzheimer Disease: AAV-hTERT (Libella Gene Therapeutics), VY-AADC (Voyager Therapeutics). 

New Buzz of Transcranial Stimulation Devices in the Neurological Disorders Market

Know which player is set to be at the forefront with its innovative technology in the Transcranial Stimulation Devices Market.

About DelveInsight

DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing end-to-end comprehensive solutions to improve their performance.  Get hassle-free access to all the healthcare and pharma market research reports through our subscription-based platform PharmDelve.

Contact Us:
Shruti Thakur 
[email protected] 
+1(919)321-6187 
www.delveinsight.com

Logo: https://mma.prnewswire.com/media/1082265/DelveInsight_Logo.jpg 


These press releases may also interest you

at 11:15
The "Europe Power Supply Equipment Market for Water Electrolysis: Focus on Application, Equipment Type, and Country - Analysis and Forecast, 2023-2032" report has been added to ResearchAndMarkets.com's offering. The Europe power supply equipment...

at 11:05
iLearningEngines Inc. ("iLearningEngines" or "the Company"), a leader in AI-powered learning automation and information intelligence for corporate and educational use, today announced that Michael Moe and Ian Davis will join the board of directors...

at 11:00
Astellas Pharma Inc. (TSE:4503, President and CEO: Naoki Okamura,...

at 10:45
The "U.S. Augmented and Virtual Reality Headset Market - A Country Analysis: Focus on Application, Product, and Country - Analysis and Forecast, 2024-2033" report has been added to ResearchAndMarkets.com's offering. The U.S. augmented and virtual...

at 10:20
The "Global Functional Milk Market - Outlook & Forecast 2024-2029" report has been added to ResearchAndMarkets.com's offering. The global functional milk market was valued at $27.00 billion in 2023 and is expected to reach a value of $41.74 billion...

at 10:15
Jazz PharmaceuticalsBy Liz HendersonLiz Henderson, Sr. Vice President Technical Operations at Jazz Pharmaceuticals discusses pioneering innovation in oncology and the importance of the manufacturing infrastructure to help achieve drug development...



News published on and distributed by: