Le Lézard
Classified in: Health, Science and technology
Subjects: Photo/Multimedia, Contract/Agreement, Product/Service

Servier and X-Chem Announce Drug Discovery Collaboration in Neurological Diseases


Servier, a global pharmaceutical Group and X-Chem, Inc., a privately held drug discovery company announced today a partnership to identify and develop novel small molecules for the treatment of neurological disorders.

Under the terms of the multi-target agreement, X-Chem will utilize its DNA-Encoded library (DEL) platform to identify novel small molecule leads directed towards Central Nervous System (CNS) targets of interest to Servier. The parties may further progress identified leads into protein-degrading chimeric molecules, with X-Chem leading the design and synthesis of bispecific degrader molecules. Servier will be responsible for advancing any promising candidates through preclinical and clinical development and retains all rights for the commercialization of any products resulting from the collaboration. X-Chem will receive research payments and is entitled to additional payments upon the achievement of certain success milestones.

"Our partnership with X-Chem supports Servier's drive for innovative drug discovery approaches towards new treatments for the benefit of patients suffering from neurological diseases. Combining our expertise gives us a truly valuable opportunity to advance the expanding internal program of drug discovery projects here at Servier, with the ultimate goal of bringing forward new and effective treatments to slow the progression of these devastating diseases," said Ross Jeggo, Head of the Neurology & Immuno-Inflammation therapeutic area at Servier.

"We are delighted that Servier has chosen X-Chem as its partner for drug discovery in this challenging therapeutic area," said Matt Clark, Chief Executive Officer at X-Chem. "We look forward to a long-term scientific collaboration with the Servier team to make advances in the treatment of neurological diseases."

About Servier

Servier is an international pharmaceutical company governed by a non-profit foundation, with its headquarters in France (Suresnes). With a strong international presence in 150 countries and a total revenue of 4.6 billion euros in 2019, Servier employs 22,000 people worldwide. Entirely independent, the Group invests on average 25% of its total revenue (excluding generics) every year in research and development and uses all its profits for its development. Corporate growth is driven by Servier's constant commitment in five areas of excellence: cardiovascular, immune-inflammatory, and neurodegenerative diseases, cancer and diabetes, as well as by its activities in high-quality generic drugs. Servier also offers eHealth solutions beyond drug development. More information: www.servier.com

About Servier BioInnovation

Servier's innovation efforts in the US are enhanced by Servier BioInnovation, a joint initiative between Servier Group R&D and Business Development & Licensing, focused on external innovation in the U.S. BioInnovation's mission includes identifying early-stage R&D opportunities and expediting BD&L activities, increasing the group's visibility and attracting talent as well as establishing R&D partnerships in key life science innovation ecosystems. https://www.servier.us/#bioinnovation

About X-Chem

X-Chem is the industry-leading provider of DNA-Encoded Library (DEL)-based discovery services. X-Chem has entered into drug discovery partnerships with numerous pharmaceutical companies, established and early-stage biotechnology companies, as well as research institutes and universities resulting in the licensing of hundreds of novel hits and leads across many target classes. X-Chem's clients and licensees include AbbVie, AstraZeneca, Bayer, Bristol-Myers Squibb, Gilead, Janssen, Maruho, MD Anderson Cancer Center, Otsuka, Roche, Vertex, among others. For further information, please visit: www.x-chemrx.com


These press releases may also interest you

at 21:45
Shop TJC Ltd. (TJC) is thrilled to announce the successful completion of its third collaboration with the iconic BBC...

at 21:32
Arctech has recently signed a contract for the 500MW Manah I power plant project in Oman, following its successful bid for the 588MW Manah II PV project in Oman earlier in 2023. This consecutive project win showcases Arctech's customized solutions...

at 21:15
Techtouch, Inc. (Headquarter: Tokyo, Japan, President/CEO: Naka Imuta) announced today that it ranked 8th in the 21st Technology Fast 50 Japan, with three-year revenue growth of 468.6%. Technology Fast 50 Japan, held annually by Deloitte Tohmatsu...

at 21:00
OKX Ventures, the investment arm of leading crypto exchange and Web3 technology company OKX, today published a report titled 'Unlocking the Infinite Potential of Crypto and AI.' The report explores the convergence of AI and crypto, a major trend in...

at 21:00
The "Strategic Storytelling for Internal Communications: Using the Power of Storytelling to Engage Employees, Manage Organizational Change, and Shape Workplace Cultures" conference has been added to  ResearchAndMarkets.com's offering. The Best...

at 20:50
Pharma (1167.HK), a clinical-stage oncology company drugging the undruggable targets, today announced its 2023 annual results. The revenue was RMB63.5 million, the R&D investment was RMB372 million, the cash and cash equivalent at the end of 2023 was...



News published on and distributed by: