The vast majority of commercially available tissue valves are xenograft valves derived from animals. Usually, the valves are porcine, meaning from a pig, or bovine, meaning from a cow. The porcine heart is most similar to the human heart and therefore represents the best anatomical fit for replacement.
The tissue of the pericardial sac is particularly well suited for a valve leaflet due to its extremely durable physical properties. Before implantation, the tissue undergoes multiple chemical treatments to make it suitable for replacement in the human heart. The tissue is sterilized so that the biological markers are removed, thereby eliminating a response from the host's immune system.
The primary advantage of tissue over mechanical valves is that tissue valves are much more biocompatible and thus a patient who receives a tissue valve does not require life-long anti-coagulation therapy. However, a disadvantage of tissue valves is that they are not as durable and typically last between 15 and 20 years before requiring replacement. Nevertheless, advances in polymer coatings have made tissue valves more durable than ever before. Furthermore, several aortic tissue valve replacement devices under development that are currently undergoing clinical trials in the U.S. or awaiting FDA approval may be implanted percutaneously.
Like any well-operating machine, the human body needs downtime in order to rest and recharge. For many, resting seems indulgent or nonproductive; but without rest, our bodies run the risk of shutting down....
? Koning Health, a leader in innovative medical imaging technology, is proud to announce the first installation of its groundbreaking Koning Vera Breast CT system in the New York City metropolitan area at Community Radiology NY on Canal Street. This...
Bringing together small business, provincial law enforcement agencies, Crime Stoppers, and government officials, Rothmans, Benson & Hedges Inc. (RBH) hosted the first ever Atlantic Forum on Contraband Tobacco....
University of Detroit Mercy (UDM) announces the new Detroit Mercy Eye Institute, located at 41555 West 12 Mile Road in Novi, Mich., which opens to patients on April 30, 2024.
University of Detroit Mercy opens new eye care center at the Novi, Mich.,...
Medline, a market-leading manufacturer and supplier of medical supplies and solutions, is pleased to announce that it is now a direct distributor for Epredia, a member of PHC Group. Epredia is a global leader in the anatomical pathology field,...