Le Lézard
Classified in: Health, Science and technology
Subjects: TDS, TRI, FVT

Iterum Therapeutics to Present Data on Prevalence of Resistant Infections and In Vitro Activity of its Novel Antibiotic Sulopenem


DUBLIN and CHICAGO, June 6, 2018 /PRNewswire/ -- Iterum Therapeutics plc (Nasdaq: ITRM), a clinical-stage pharmaceutical company developing anti-infectives against multi-drug resistant pathogens, will present four posters at the American Society of Microbiology MICROBE meeting in Atlanta from June 7 - 10, 2018.

Poster 695, June 8

Impact of Initial Inappropriate Antibiotic Therapy on Outcome for Outpatient Urinary Tract Infection Due to Fluoroquinolone Non-Susceptible Uropathogens

Poster 569, June 10

Sulopenem Activity Against Enterobacteriaceae Isolates from Patients with Urinary Tract Infection

Poster 570, June 10

Prediction of Sulopenem Activity Against Enterobacteriaceae Using Ertapenem as a Surrogate

Poster 568, June 10

In Vitro Activity of Sulopenem, an Oral Penem, Against Escherichia coli Isolated from Urine Specimens of Patients Across Canada in 2014-2016

"Quinolones, the most commonly prescribed class of antibiotics for treatment of uncomplicated urinary tract infections, are resulting in clinical failures at an alarming rate," said Michael Dunne, M.D., Chief Scientific Officer at Iterum Therapeutics. "Given the resistance to quinolones in the community, new treatment strategies, including new antibacterial therapies, are urgently needed."

"We believe sulopenem, with its spectrum of in vitro activity has considerable potential as an important new treatment option, in an oral and intravenous formulation, to help patients and physicians better address infections caused by resistant pathogens."

About Iterum Therapeutics plc

Iterum Therapeutics plc is a clinical-stage pharmaceutical company dedicated to developing differentiated anti-infectives aimed at combatting the global crisis of multi-drug resistant pathogens to significantly improve the lives of people affected by serious and life-threatening diseases around the world. Iterum Therapeutics is advancing its first compound, sulopenem, a novel penem anti-infective compound with oral and IV formulations that has demonstrated potent in vitro activity against a wide variety of gram-negative, gram-positive and anaerobic bacteria resistant to other antibiotics. Iterum Therapeutics has received QIDP designations for its oral and IV formulations for the treatment of uUTI, complicated urinary tract infection and complicated intra-abdominal infection. For more information, please visit http://www.iterumtx.com.

Forward-looking Statements
This press release contains forward-looking statements. These forward-looking statements include, without limitation, statements regarding the development and therapeutic potential of sulopenem and the timing, progress and results of clinical trials. In some cases, forward-looking statements can be identified by words such as "may," "believes," "intends," "seeks," "anticipates," "plans," "estimates," "expects," "should," "assumes," "continues," "could," "will," "future," "potential" or the negative of these or similar terms and phrases.  Forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause Iterum Therapeutics' actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. Forward-looking statements include all matters that are not historical facts. Actual future results may be materially different from what is expected due to factors largely outside Iterum Therapeutics' control, including the results of clinical trials, clinical trial patient enrolment, changes in regulatory requirements or decisions of regulatory authorities, commercialization plans and timelines if approved, the actions of third-party clinical research organizations, suppliers and manufacturers and other factors discussed under the caption "Risk Factors" in the final prospectus for Iterum Therapeutics' initial public offering, which was filed with the Securities and Exchange Commission (the "SEC") on May 25, 2018, and other documents filed with the SEC from time to time. Forward-looking statements represent Iterum Therapeutics' beliefs and assumptions only as of the date of this press release. Except as required by law, Iterum Therapeutics assumes no obligation to update these forward-looking statements publicly, or to update the reasons actual results could differ materially from those anticipated in the forward-looking statements, even if new information becomes available in the future.

Contact:
Jeff Schaffnit
Chief Commercial Officer
312-778-6076
[email protected]

 

SOURCE Iterum Therapeutics plc


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