Le Lézard
Classified in: Health, Science and technology
Subject: TRI

MYR Pharma Announces Completion of Active Treatment Phase in MYR 203 Clinical Trial of Myrcludex B


BURGWEDEL, Germany, Feb. 22, 2018 /PRNewswire/ -- MYR Pharma GmbH today announced the completion of the 48-week-long active treatment phase in MYR 203 clinical trial, a part of Phase 2b program investigating Myrcludex B in combination with pegylated interferon (PEG INF) in chronic hepatitis Delta (HDV) infection. A total of 60 subjects enrolled into this study in 7 centers in Russia were randomized in four groups to receive PEG INF, Myrcludex B monotherapy, and combinations of PEG INF with two different doses of Myrcludex B, respectively.

Commenting on the announcement, MYR Pharma's Chief Medical Officer Dr. Alexander Alexandrov said: "Myrcludex B was very well tolerated with no SAEs attributed to the study drug, confirming the excellent safety profile of the drug that we observed in previous clinical studies." He further commented: "All patients on the combination therapy have by now completed 48 weeks of treatment. We are currently evaluating efficacy readouts from the study."

"Myrcludex B recently demonstrated encouraging results in cirrhotic and interferon non-responder population in MYR 202 clinical trial. The ongoing MYR 203 study will provide an insight as to whether add-on treatments with Myrcludex B can improve suboptimal outcomes of the current standard-of-care interferon treatment," said Heiner Wedemeyer, MD, Professor at the Essen University Hospital and Chairman of MYR Pharma's Clinical Advisory Board.

The patients in MYR 203 are now undergoing a 24-week follow up period. The company expects to announce the results of the study in the mid-2018.

About Myrcludex B

Myrcludex B is a first-in-class entry inhibitor for the treatment of chronic hepatitis B (HBV) and its co-infection hepatitis Delta. The drug inhibits the recently identified HBV receptor on the hepatocyte surface and prevents the infection of the healthy cells and viral spreading within the liver. Myrcludex has shown an excellent safety profile and antiviral efficacy in several clinical trials. The drug has received Orphan Designation for treatment of HDV infection from the EMA and FDA, and PRIME scheme eligibility from the EMA. Myrcludex B was originally developed at the University of Heidelberg (Germany) and INSERM (France) and is currently one the most clinically advanced novel approaches to the treatment of HBV and HDV.

About MYR GmbH

MYR Pharma GmbH is a German clinical stage biotechnology company focused on the development of drugs for the treatment of chronic hepatitis B and Delta virus infections.

CONTACT: Alexey Eliseev, 1-617-953-0767

SOURCE MYR Pharma


These press releases may also interest you

at 21:45
Shop TJC Ltd. (TJC) is thrilled to announce the successful completion of its third collaboration with the iconic BBC...

at 21:32
Arctech has recently signed a contract for the 500MW Manah I power plant project in Oman, following its successful bid for the 588MW Manah II PV project in Oman earlier in 2023. This consecutive project win showcases Arctech's customized solutions...

at 21:15
Techtouch, Inc. (Headquarter: Tokyo, Japan, President/CEO: Naka Imuta) announced today that it ranked 8th in the 21st Technology Fast 50 Japan, with three-year revenue growth of 468.6%. Technology Fast 50 Japan, held annually by Deloitte Tohmatsu...

at 21:00
OKX Ventures, the investment arm of leading crypto exchange and Web3 technology company OKX, today published a report titled 'Unlocking the Infinite Potential of Crypto and AI.' The report explores the convergence of AI and crypto, a major trend in...

at 21:00
The "Strategic Storytelling for Internal Communications: Using the Power of Storytelling to Engage Employees, Manage Organizational Change, and Shape Workplace Cultures" conference has been added to  ResearchAndMarkets.com's offering. The Best...

at 20:50
Pharma (1167.HK), a clinical-stage oncology company drugging the undruggable targets, today announced its 2023 annual results. The revenue was RMB63.5 million, the R&D investment was RMB372 million, the cash and cash equivalent at the end of 2023 was...



News published on and distributed by: